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. 2022 Nov 2;65(22):15282–15299. doi: 10.1021/acs.jmedchem.2c01218

Table 1. DC50 (nM) and Dmax (%) Values of Compounds 2729, 3234, and 37 after 8 h Treatmentsa.

compound DC50 (nM) Dmax (%)
27 97.1 88
28 134.0 79
29 184.0 86
32 239.0 81
33 89.9 78
34 60.0 94
37 62.0 86
a

Values were calculated using densitometry of Western blots shown in Figures 7 and 8B. Dmax is expressed as maximal % of reduction toward DMSO control lane.