| Ciloa (France) |
Ciloa
is an exosome spin-off company from
the French National Center for Scientific Research
and the University of Montepellier. Ciloa is dedicated to in vivo development of recombinant exosomes for therapeutic
and preventative applications. Their recombinant exosomes allow for
loading of two types of protein cargo: the first one, at the surface
for disease targeting; the second one, as the cargo inside the exosome
to deliver a signal for modification,
multiplication, or death.440
|
| Clara Biotech (USA) |
Clara provides exosome
isolation using their developed ExoRelease
Isolation Platform and characterization as a service for researchers. They have developed a starter kit version of their ExoRelease Isolation Platform for researchers
to perform isolation of exosomes in their own lab, as well. They also
offer the services of nanoparticle tracking analysis for exosome characterization,
exosome proteomic analysis, exosome nucleic acid analysis, and exosome
imaging.441
|
| Creative
Biolabs (USA) |
Creative Biolabs offers a wide range of exosome-related research services.
These services include
exosome isolation, purification, characterization, quantification,
profiling, proteomics, lipidomic and metabolomics assays, RNA sequencing,
exosome engineering and manufacturing, and exosome antibody development
and display and have in vitro and in vivo model platforms.442
|
| EverZom (France) |
EverZom is an exosome service
company who provides a large panel
of services for exosome development
including exosome production, characterization, isolation/purification, and engineering services.443
|
| Exosome Plus (Republic of Korea) |
Exosome
Plus manufactures MSC-derived exosomes, plant-derived
exosomes, human-derived exosomes, and animal-derived exosomes. Their
therapy platform is called ExoThera, and they are hoping to develop
their liquid biopsy platform to diagnose 11 major cancers using body
fluid exosomes. They also sell an exosome isolation kit called Exo2D
and an EV characterization system called ExoCope which is a single exosome multicolor fluorescence colocalization
and particle tracking analysis system.444
|
| Exosomics (Italy) |
Exosomics
offers the services of exosome isolation and characterization,
nucleic acid extraction, protein separation, nucleic acid analytical
assays, and protein analytical assays.445 They also offer kits for researchers to use in their lab including
exosome purification kits and exosome-based reference standards.446
|
| FUJIFILM Wako Chemicals
USA Corporation (USA) |
FUJIFILM offers many different
exosome kits and products including
exosome isolation kits, ELISA kits, and flow cytometry kits. They
also offer exosome marker antibodies, blocking reagents, purified
exosomes, exosome cell cultures, and labware for researchers to utilize
in their own laboratories.447
|
| HansaBioMed Life Sciences (Estonia) |
HansaBioMed
is entirely dedicated to research and development
in the exosome sciences field. Their services include purification
of exosomes from condition media, biofluids, or plant extracts, exosome
characterization, biomarker assessment by mass spectrometry, and RNA
sequencing. They also sell a broad
range of purified exosomes, tools for purification, enrichment, and
characterization.448
|
| Lonza (USA) |
Lonza acquired HansaBioMed Life Sciences
in 2017. More recently
in 2021, Lonza acquired Codiak’s (Therapeutic exosome company)
manufacturing facility and is the strategic manufacturing partner
for Codiak’s pipeline. Additionally, in 2021, they announced
they acquired Exosomics.449
|
| NanoFCM (UK) |
NanoFCM has a commercial product
available called the flow nanoanalyzer which is a high-sensitivity flow cytometry for exosome analysis. They also
offer exosome sample analysis service.450
|
| NanoView Biosciences (USA) |
Nanoview Biosciences creates exosome products to help with
exosome characterization. Their ExoView R200 product allows for automated
exosome measurement. Their ExoView kits allow for standard or customizable
assays for purification of free exosomes. The ExoView chip washer
offers reliable hands-free sample preparation, along with their ExoView
software suite that offers reporting of exosome size, counts, and
biomarker colocalization.451
|
| ReNeuron (UK) |
Exosomes produced by the ReNeuron’s stem cell lines
or via its induced pluripotent stem cell platform have the possibility
to be manufactured through a scalable
process and loaded with a broad range
of payloads, such as nucleic acids, proteins, as well as small molecules.
They are in collaboration with universities, global pharma, and biotech
companies in various stages from discovery to in vivo late-stage studies.452
|
| RoosterBio (USA) |
RoosterBio is dedicated to accelerating
exosome product and
process development for exosome therapeutics. They have developed
an extensive panel of exosome analytical methods to support this including
exosome NTA for characterization, purification, protein analysis,
surface marker expression, cytosolic marker expression, miRNA quantitation
and analysis, lipid content, albumin contamination, CD63 quantitation,
and scratch assays for wound healing.453 They also produce exosome production media for both research and
manufacturing.454
|
| Systems Biosciences (USA) |
Exosome research products
and services are offered by Systems
Biosciences to help advance exosome research studies. They offer exosome
isolation, detection, quantification, labeling, biomarker discovery,
engineering, and design kits and products.455
|
| ThermoFisher Scientific (USA) |
ThermoFisher Scientific is a world
leader in serving science, staying one step ahead for advancing
science, and their products for exosomes are no different. They offer a wide range of exosome products for isolation, analysis,
and cargo isolation. They also offer exosome depleted fetal bovine
serum along with reagents for automated preparation products for exosome
analysis.456
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