Table 6.
Association between risk factors and outcomes of gastrointestinal complications and operations in Crohn's disease.
| Gastrointestinal complications | Surgery | |||||||
|---|---|---|---|---|---|---|---|---|
| Total | Yes | P value | Missing | Total | Yes | P value | Missing data | |
| Age at presentation | ||||||||
| <16 years | 54 (22.4) | 42 (77.8) | .5787 | 8 | 56 (23) | 29 (51.8). | 3023 | 5 |
| 17-40 years | 169 (70.1) | 142 (84) | 169 (69.3) | 82 (48.5) | ||||
| > 40 years | 18 (7.5) | 15 (83.3) | 19 (7.8) | 6 (31.6) | ||||
| Disease burden | ||||||||
| Systemic comorbidities | 102 (42.3) | 80 (78.4) | .1466 | 8 | 104 (42.6) | 54 (51.9) | .2844 | 5 |
| Gastrointestinal comorbidities | 39 (16.2) | 27 (69.2) | .0164 | 8 | 40 (16.4) | 16 (40) | .2710 | 5 |
| Extensive disease | 126 (55) | 108 (85.7) | .3947 | 20 | 125 (54.1) | 63 (50.4) | .7290 | 18 |
| Perianal symptoms | 30 (12.8) | 25 (83.3) | .8951 | 15 | 30 (12.7) | 8 (26.7) | .0119 | 12 |
| Extraintestinal manifestation | 39 (16.3) | 32 (82.1) | .8245 | 10 | 39 (16.5) | 17 (43.6) | .4642 | 12 |
| Family history | 9 (4.1) | 7 (77.8) | .6504 | 30 | 9 (4) | 5 (55.6) | .7471 | 27 |
| Smoking | 41 (17.8) | 36 (87.8) | .4106 | 19 | 42 (17.9) | 24 (57.1) | .2404 | 14 |
| Treatment | ||||||||
| Biological treatment | 209 (87.8) | 180 (86.1) | .0002 | 11 | 209 (87.8) | 103 (49.3) | .2525 | 11 |
| Steroid treatment | 68 (28.6) | 53 (77.9) | .2118 | 11 | 70 (29.4) | 31 (44.3) | .4713 | 11 |
| Sex | ||||||||
| Female | 95 (39.4) | 72 (75.8) | .0251 | 8 | 96 (39.3) | 42 (43.8) | .2901 | 5 |
| Male | 146 (60.6) | 127 (87) | 148 (60.7) | 75 (50.7) | ||||
Data are n (%).