Table 3. Univariate and multivariate ordinal logistic regression analysis for LV improvement, no change or deterioration post TAVI.
| Predictor | Coeff. | SE coeff. | z | p-value | Odds ratio | 95% CI (lower) | 95% CI (upper) |
|---|---|---|---|---|---|---|---|
| Univariate analysis | |||||||
| Age | 0.011 | 0.011 | 1.02 | 0.308 | 1.01 | 0.99 | 1.03 |
| Sex (F) | 0.115 | 0.159 | 0.72 | 0.47 | 1.12 | 0.82 | 1.53 |
| BMI | −0.007 | 0.017 | −0.04 | 0.968 | 1.00 | 0.97 | 1.03 |
| Pre-CAD-1 | −0.127 | 0.211 | −0.6 | 0.547 | 0.88 | 0.58 | 1.33 |
| Pre-CAD-2 | 0.141 | 0.222 | 0.64 | 0.525 | 1.15 | 0.75 | 1.78 |
| Pre-CAD-3 | −0.271 | 0.250 | −1.08 | 0.279 | 0.76 | 0.47 | 1.25 |
| Previous MI | 0.229 | 0.199 | 1.15 | 0.251 | 1.26 | 0.85 | 1.86 |
| Hypertension | −0.095 | 0.162 | −0.59 | 0.558 | 0.91 | 0.66 | 1.25 |
| Diabetes mellitus | 0.038 | 0.171 | 0.22 | 0.824 | 1.04 | 0.74 | 1.45 |
| Smoking, past | −0.197 | 0.181 | −1.09 | 0.277 | 0.82 | 0.58 | 1.17 |
| Smoking, current | −0.090 | 0.285 | −0.32 | 0.751 | 0.91 | 0.52 | 1.60 |
| AF, paroxysmal | 0.266 | 0.193 | 1.38 | 0.167 | 1.31 | 0.89 | 1.90 |
| AF, chronic | 0.127 | 0.261 | 0.49 | 0.626 | 1.14 | 0.68 | 1.89 |
| Frailty | 0.102 | 0.161 | 0.63 | 0.527 | 1.11 | 0.81 | 1.52 |
| Logistic EuroSCORE | 0.038 | 0.008 | 4.66 | <0.001 | 1.04 | 1.02 | 1.05 |
| GFR | −0.006 | 0.004 | −1.71 | 0.087 | 0.99 | 0.99 | 1.00 |
| Pre-AV annular area | <0.001 | <0.001 | 0.03 | 0.975 | 1.00 | 1.00 | 1.00 |
| Pre-AV mean gradient | −0.007 | 0.004 | −1.56 | 0.118 | 0.99 | 0.98 | 1.00 |
| Pre-TAPSE | −0.086 | 0.0567 | −1.52 | 0.128 | 0.92 | 0.82 | 1.03 |
| Pre-MR | 0.524 | 0.223 | 2.35 | 0.019 | 1.69 | 1.09 | 2.62 |
| Pre-RVSP | 0.027 | 0.010 | 2.84 | 0.005 | 1.03 | 1.01 | 1.05 |
| Pre-LVFn-II | 3.315 | 0.307 | 10.81 | <0.001 | 27.52 | 15.09 | 50.20 |
| Pre-LVFn-III | 3.624 | 0.333 | 10.88 | <0.001 | 37.50 | 19.52 | 72.04 |
| Pre-LVFn-IV | 4.250 | 0.420 | 10.12 | <0.001 | 70.10 | 30.77 | 159.69 |
| Post-PPM | 0.534 | 0.265 | 2.02 | 0.004 | 1.71 | 1.02 | 2.87 |
| Post-PVR | 0.163 | 0.143 | 1.14 | 0.254 | 1.18 | 0.89 | 1.56 |
| Multivariate analysis | |||||||
| Const (1) | −3.591 | 0.653 | −5.50 | <0.001 | – | – | – |
| Const (2) | 0.959 | 0.570 | 1.68 | 0.093 | – | – | – |
| Logistic EuroSCORE | −0.009 | 0.014 | −0.65 | 0.515 | 0.99 | 0.97 | 1.02 |
| Pre-MR | −0.094 | 0.398 | −0.24 | 0.813 | 0.91 | 0.42 | 1.99 |
| Pre-RVSP | 0.021 | 0.011 | 1.85 | 0.064 | 1.02 | 1.00 | 1.04 |
| Pre-LVFn-II | 2.972 | 0.421 | 7.06 | <0.001 | 19.54 | 8.56 | 44.61 |
| Pre-LVFn-III | 3.299 | 0.451 | 7.31 | <0.001 | 27.08 | 11.18 | 65.59 |
| Pre-LVFn-IV | 4.199 | 0.600 | 7.0 | <0.001 | 66.62 | 20.55 | 216.05 |
| Post-PPM | 0.187 | 0.423 | 0.44 | 0.659 | 1.21 | 0.53 | 2.76 |
| AF: atrial fibrillation; BMI: body mass index; GFR: glomerular filtration rate; MI: myocardial infarction; n: number of vessels with disease; Post-PPM: post-TAVI permanent pacemaker implantation; Post-PVR: post-TAVI paravalvular leak (graded); Pre-AV: pre-TAVI aortic valve; Pre-CAD-n: pre-TAVI coronary artery disease; Pre-LVFn: pre-TAVI LV function grade; Pre-MR: pre-TAVI mitral regurgitation; Pre-TAPSE: pre-TAVI tricuspid annular plane systolic excursion; Pre-RVSP: pre-TAVI right ventricular systolic pressure | |||||||