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Summary of patient cohort for DNA methylation analysis
| Healthy controls | COVID19 severe patients | p value | |
|---|---|---|---|
| Number | 11 | 48 | - |
| Age (mean ± SD) | 50 ± 11.16 | 60 ± 11.96 | 0.0042 |
| Sex (% female) | 36.4 | 25 | 0.710 |
| SOFA | 0 | 5 ± 2.97 | 2.4e − 07 |
| IL-6 (pg/ml) (mean ± SD) | NA | 316.94 ± 1238.82 | - |
| Days in ICU (mean ± SD) | NA | 6 ± 5.93 | - |
| Treated with dexamethasone (%) | NA | 52.08 | - |
| Obesity (%) | NA | 27.03 | - |
| Hypertension (%) | NA | 56.25 | - |
| Death (%) | NA | 33.33 | - |
| Mechanical ventilation (%) | NA | 93.75 | - |
