FIG. 5.
Antibody response of hamsters immunized with leptospiral OMPs. Hamsters were immunized with E. coli membrane fractions with (solid lines) and without (broken lines) OmpL1-M, LipL41-M, or a combination of both. Antibody levels were determined by ELISA against purified His6-OmpL1 (A) and His6-LipL41 (B) fusion proteins. Antibody levels were lower in hamsters immunized with both antigens than in those immunized with single antigens.