Table 1.
Overview of Study Participants With Chronic HCV Infection at the First LSM Visit (n = 1323)*
| Characteristic | Value |
|---|---|
| Median age (IQR), y | 49 (43–54) |
| Sex | |
| Male | 936 (71) |
| Female | 387 (29) |
| Race | |
| Black | 1085 (82) |
| Non-Black | 238 (18) |
| AUDIT category † | |
| None | 587 (44) |
| Harmful/hazardous alcohol use | 295 (23) |
| Severe alcohol use/dependence | 439 (33) |
| Injection drug use in previous 6 mo | |
| No | 606 (46) |
| Yes | 714 (54) |
| Methadone use in previous 6 mo | |
| No | 958 (73) |
| Yes | 362 (27) |
| BMI ‡ | |
| Underweight/normal | 660 (51) |
| Overweight | 401 (31) |
| Obese | 238 (18) |
| Number of comorbidities § | |
| 0 | 626 (47) |
| 1 | 554 (42) |
| ≥2 | 135 (10) |
| HIV status | |
| Negative | 867 (66) |
| Positive, undetectable viral load | 235 (18) |
| Positive, detectable viral load | 217 (16) |
| Median log LSM (IQR), kPa | 1.95 (1.72–2.29) |
| LSM ≥12.3 kPa (cirrhosis) | |
| Yes | 194 (15) |
| No | 1129 (85) |
AUDIT = Alcohol Use Disorders Identification Test; BMI = body mass index; HCV = hepatitis C virus; LSM = liver stiffness measure.
Data are numbers (percentages) unless otherwise indicated. Some frequencies might not sum to the total because of missing values.
AUDIT scores between 8 and 14 were classified as harmful/hazardous alcohol use, and scores ≥15 were classified as severe alcohol use/dependence.
BMI <25 kg/m2 was classified as underweight/normal, 25–29.9 kg/m2 was classified as overweight, and ≥30 kg/m2 was classified as obese. Because there was a small number of underweight participants, they were grouped with those with normal weight.
Comorbidities were based on either 1) participants self-reporting that they had ever been told by a physician that they had kidney disease, diabetes, or hypertension, or 2) diagnostic criteria–based clinical/laboratory measurements (chronic kidney disease: estimated glomerular filtration rate <60 mL/min/1.73 m2; diabetes: hemoglobin A1c level >6.5%; hypertension: blood pressure >150/90 mm Hg for persons aged ≥60 y or >140/90 mm Hg for those aged <60 y).