Table 2.
Comparison between clinically active and inactive LVV patients
| Characteristics | Active LVV (n = 125) | LVV in remission (n = 351) | P-value |
|---|---|---|---|
| Age at PET/CT, mean (s.d.), years | 49.9 (19.1) | 51.0 (16.8) | 0.534 |
| PETVAS, mean (s.d.) | 10.5 (7.9) | 4.4 (5.5) | <0.0001 |
| ESR, mean (s.d.), mm/1 ha | 54.6 (34.5) | 20.2 (15.1) | <0.0001 |
| CRP, mean (s.d.), mg/dlb | 5.4 (10.4) | 0.8 (1.4) | <0.0001 |
| Presence of at least one symptom suggestive for active vasculitis, n (%)c | 95 (76.0)d | 0e | <0.0001 |
| Patients on prednisone, n (%) | 111 (88.8) | 191 (54.4) | <0.0001 |
| Prednisone dose, mean (s.d.), mg/day | 31.6 (19.1) | 11.2 (11.9) | <0.0001 |
| Patients on prednisone >20 mg/day, n (%) | 71 (56.8) | 31 (8.8) | <0.0001 |
| Disease duration at PET/CT scans, mean (s.d.), months | 37.4 (49.9) | 68.1 (37.4) | <0.0001 |
a
Missing = 16.
b
Missing = 11.
c
Missing = 8.
d
30 patients without any symptoms suggestive for active vasculitis were classified as active according to the Kerr/NIH criteria (elevated ESR and/or CRP and angiographic features indicative of vasculitis).
e
13 patients (3.7%) in LVV remission had isolated fatigue associated with elevated ESR or CRP.