TABLE 2.

Levels of IL-6 in plasma^a

Time (h)	IL-6 level (ng/ml) (mean ± SEM) in indicated treatment group
	Sham	25G	21G
2	5 ± 3	15 ± 5	30 ± 17
4	27 ± 6	364 ± 116	303 ± 125b
8	6 ± 2.5	435 ± 150	1,390 ± 781b
12	5 ± 1	117 ± 50	1,413 ± 932b
16	19 ± 15	43 ± 21	251 ± 93b
20	0.32 ± 0.1	47 ± 12	183 ± 128b
24	0.1 ± 0.07	19 ± 6	196 ± 110b

^aLevels were elevated in all mice that underwent CLP. Similar to the 18G-treated group, the 21G-treated group had substantial IL-6 elevations that were significantly higher than those of the sham treatment group after 4 h. 

^bP < 0.05 for 21G versus sham treatment groups.