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Higher total caloric intake in adolescents with NAFLD correlates with worsening biochemical disease (A). A higher proportion of total caloric intake from fructose and carbohydrates correlates with worsening hepatic inflammation on biopsy (B, C). In addition, A higher proportion of total caloric intake from carbohydrate, glucose and added sugars correlates worsening overall histologic disease severity, as indicated by higher NAS Summary scores (D, E, F).
