TABLE 1.

Enhancement of TNF-α production by DAG kinase inhibitor^a

Stimulus	TNF-α (pg/ml)
R59949	27.9 ± 3.2b
SEB	546.7 ± 1.2
SEB + R59949	711.5 ± 20.5b

^aMixed cells were plated in four replicates and incubated with 1 μM R59949 for 60 min followed by stimulation with 10 ng of SEB per ml for 20 h. Media were collected and analyzed in duplicate for TNF-α. 

^bStatistical analysis (t test) of significant differences compared to SEB alone showed P < 0.001.