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. 2022 Dec;28(12):2463–2471. doi: 10.3201/eid2812.221136

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Emerging Infectious Diseases is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.

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Antibody titers and percentage of population positive for antibodies against orthopoxviruses in France in study of seroprevalence and infection susceptibility in France, Bolivia, Laos, and Mali. Serum samples from 4,448 persons were tested for antibodies against both vaccinia and cowpox virus and an orthopoxvirus neutralization titer (ONT) was determined. A, B) Overall comparison of ONT geometric mean ±SD (A) and percentage of positive participants (ONT>20) (B) according to decade of birth (p values are described in Appendix Table 1). C, D) Comparisons of ONT geometric mean ±SD (C) and percentage of positive persons (ONT>20) (D) between male and female participants according to decade of birth. E, F) Comparisons of ONT geometric mean ±SD (E) and percentage of positive persons (ONT>20) (F) for populations in 4 different regions of France according to their decade of birth (p values are described in Appendix Table 2). Mann-Whitney tests were used to determine geometric means ±SD; Fisher exact tests were used to compare percentage of positive persons. A p value <0.05 was considered significant.