Table 4.
Univariate and multivariable logistic regression models of disease severity.
| Univariate analysis | Multivariable analysis | |||
|---|---|---|---|---|
| OR (95% CI) | p | OR (95% CI) | p | |
| Age at onset | 0.993 (0.973–1.013) | 0.493 | ||
| Gender | 1.906 (1.015–3.579) | 0.045* | 1.644 (0.80–3.378) | 0.176 |
| Hypertension | 0.491 (0.157–1.537) | 0.222 | ||
| Diabetes | 0.938 (0.129–6.828) | 0.950 | ||
| PT | 1.332 (1.027–1.726) | 0.031* | 1.109 (0.823–1.494) | 0.496 |
| APTT | 0.994 (0.954–1.036) | 0.777 | ||
| Fibrinogen | 1.004 (0.814–1.238) | 0.971 | ||
| TT | 0.967 (0.826–1.131) | 0.672 | ||
| D-dimer | 2.557 (1.116–5.856) | 0.026* | 2.631 (1.018–6.802) | 0.046* |
| WBC | 1.195 (1.084–1.317) | <0.001* | ||
| RBC | 0.733 (0.405–1.328) | 0.306 | ||
| Hemoglobin | 0.987 (0.968–1.006) | 0.170 | ||
| Platelet | 0.999 (0.995–1.003) | 0.627 | ||
| Neutrophil | 1.233 (1.111–1.368) | <0.001* | 1.2 (1.07–1.345) | 0.002* |
| Lymphocyte | 0.865 (0.680–1.100) | 0.236 | ||
| Monocytes | 0.892 (0.623–1.276) | 0.531 | ||
| Eosinophils | 0.003 (0–0.168) | 0.005* | 0.099 (0.002–5.024) | 0.249 |
| Basophil | 0.004 (0–14.446) | 0.189 | ||
| Calcium | 0.098 (0.011–0.901) | 0.040* | 0.328 (0.038–2.799) | 0.308 |
| CRP | 1.018 (0.988–1.049) | 0.249 | ||
WBC were not included in the multivariate analysis because of the strong correlation between WBC and neutrophils (r = 0.933, p < 0.001).
CI, confidence interval; PT, prothrombin time; APTT, activated partial thrombin time; TT, thrombin time; WBC, white blood cell; RBC, red blood cell; CRP, C-reaction protein.
*
p < 0.05.