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. 2022 Nov 15;13:1002828. doi: 10.3389/fpsyt.2022.1002828

TABLE 1.

Demographics of participants.

Variables Discovery set Validation set


Control MDDa P-value Control MDD Remission P-value
Number of participants 26 32 35 44 35
Age (mean ± SDb) 51 ± 8 52 ± 19 0.491d 65 ± 6 54 ± 15 62 ± 14 <0.05e
Sex (male/female) 6/20 12/20 0.238f 6/29 11/33 7/28 0.685f
Drug treated (DT)/non-drug treated (NDT) 14/18 26/18
HAMD-17c (mean ± SDb) 20 ± 5 21 ± 6

aMDD, major depressive disorder; bSD, standard deviation; cHAMD-17, Hamilton Depression Scale (17-item); dMann–Whitney U-test; eone-way ANOVA with Dunnet t-test for multiple comparison (MDD vs Control p-value and MDD vs Remission p-value were < 0.05, Control vs Remission p-value = 0.616); and fChi-square test.