Fig 5. Spatial frequency responses of putative midget cells.

Fifteen cells in M3 serving the central foveal cones were identified as L-M or M-L opponent (Fig 3D). Each cell is numbered L1-11 or M1-4 based on whether the suspected center cone was an L or M cone. The red points (circles, Week 1), blue points (triangles, Week 2), and green points (squares, Week 3) are measurements from three different experiments each one week apart. The solid orange line in each panel is the average response for that particular cell across all three experiments. The vertical axis is a response metric where the mean baseline fluorescence is subtracted from the fluorescence under stimulation and divided by the fluorescence under stimulation at the peak spatial frequency (see Methods). The error bars show the standard error at each data point, which represents the error in obtaining the signal and background needed to calculate the metric. Additional spatial frequency responses of cells from the large imaging FOV (S5 Fig) and non-midget RGCs (S6 Fig) can be found in the supplement.