Table Table.

Characteristics of Included Studies

Reference	Country	Period	Design	Total population (men/women)	Cases (men/women)	Outcome	Early‐onset dementia cutoff, y	Age, mean±SD, y
Bunch et al 201021	United States	Not reported	Cohort	37 025 (10 161 incident AF)	1535 cases of dementia (all ages); dementia for those aged <70 y not reported	Incidence of dementia	<70	60.6±17.9 (57.8±18.9 AF free; 68.1±12.2 AF)
Chen et al 202129	Taiwan	Jan 2001–Dec 2013	Case‐cohort AF and AF free	200 130 (100 065/100 065)	1897 (919/978)	Incidence of dementia (overall and for AD and VaD)	<65	72.5±12.5
de Bruijn et al 201522	The Netherlands	Sept 2014–Apr 2015	Cohort	6194	932 cases of dementia (all ages); dementia for those aged <70 y not reported	Incidence of dementia	<67	68.3
Kim et al 201930	South Korea	2005–2012	Cohort	262 611 (10 435 incident AF)	638	Incidence of dementia	<70	70.7±5.4 (AF); 71.7±5.7 (AF free)
Kim et al 202031	South Korea	2005–2010	Cohort	428 262 (232 513/195 749)	1112 (955 censoring for stroke)	Incidence of AF and dementia	<65	61.7±9.9 (AF) 55.5±9.1 (AF free)
Liao et al 201532	Taiwan	Jan 1996–Dec 2011	Case‐cohort AF and AF free	665 330 (372 000/293 330)	56 901 cases of dementia (all ages); dementia for those aged <70 y not reported	Incidence of dementia	<65	70.3±13.0 (AF and AF free)

AD indicates Alzheimer dementia; AF, atrial fibrillation; and VaD, vascular dementia.