Table 2.

The table summarizes the META data statistics

	${\mathrm{C}}_0$	${\mathrm{C}}_1$	${\mathrm{C}}_2$	P-value
$\mathrm{Age}\mathrm{ }\left(\mathrm{years}\right),\mathrm{ }\mathrm{mean}\mathrm{ }\left(\mathrm{SD}\right)$	72.00 (12.98)	72.00 (13.17)	55.00 (16.27)	<0.001*
$\mathrm{Amiodarone},\mathrm{ }n\mathrm{ }\left(\mathrm{\%}\right)$	197 (2.73)	165 (2.53)	2013 (0.51)	<0.001*
$\mathrm{Diuretics},\mathrm{ }n\mathrm{ }\left(\mathrm{\%}\right)$	2334 (32.3)	2072 (31.78)	85 025 (21.36)	<0.001*
$\mathrm{Sex},\mathrm{ }\mathrm{male},\mathrm{ }n\mathrm{ }\left(\mathrm{\%}\right)$	4011 (55.52)	3361 (51.55)	149 755 (37.61)	<0.001*
$\mathrm{PAH},\mathrm{ }n\mathrm{ }\left(\mathrm{\%}\right)$	3504 (48.5)	3198 (49.05)	143 902 (36.14)	<0.001*
$\mathrm{Chagas},\mathrm{ }n\mathrm{ }\left(\mathrm{\%}\right)$	432 (5.98)	384 (5.86)	9634 (2.42)	<0.001*
$\mathrm{Beta}\mathrm{ }\mathrm{blockers},\mathrm{ }n\mathrm{ }\left(\mathrm{\%}\right)$	878 (12.15)	740 (11.35)	31 419 (7.89)	<0.001*
$\mathrm{Family}\mathrm{ }\mathrm{CHD},\mathrm{ }n\mathrm{ }\left(\mathrm{\%}\right)$	1005 (13.91)	923 (14.16)	50 140 (12.59)	<0.001*
$\mathrm{MI},\mathrm{ }n\mathrm{ }\left(\mathrm{\%}\right)$	121 (1.67)	95 (1.46)	3207 (0.81)	<0.001*
$\mathrm{COPD},\mathrm{ }n\mathrm{ }\left(\mathrm{\%}\right)$	86 (1.19)	57 (0.87)	2423 (0.61)	<0.001*
$\mathrm{DM},\mathrm{ }n\mathrm{ }\left(\mathrm{\%}\right)$	561 (7.76)	542 (8.31)	28 633 (7.19)	<0.001*
$\mathrm{Obesity},\mathrm{ }n\mathrm{ }\left(\mathrm{\%}\right)$	335 (4.64)	391 (6.0)	22 868 (5.74)	0.001*
$\mathrm{Dyslipidaemia},\mathrm{ }n\mathrm{ }\left(\mathrm{\%}\right)$	287 (3.97)	268 (4.11)	15 363 (3.86)	0.031*
$\mathrm{Calcium}\mathrm{ }\mathrm{blockers},\mathrm{ }n\mathrm{ }\left(\mathrm{\%}\right)$	0 (0.0)	0 (0.00)	95 (0.01)	0.155
$\mathrm{Smoking},\mathrm{ }n\mathrm{ }\left(\mathrm{\%}\right)$	367 (5.08)	387 (5.94)	24 627 (6.19)	0.486

It includes a summary for the baseline recordings in $C_0,\mathrm{ }{C}_1,\mathrm{ }{C}_2$. With examples in $C_0$ being AF, examples in $C_1$ developing AF within 5 years and examples in $C_2$ not developing AF within 5 years. Mann–Whitney rank test was performed between ${\mathrm{C}}_1$ and ${\mathrm{C}}_2$. Features ordered from most to least significant according to their P-value. The sign * indicates statistical significance (Mann–Whitney rank test, P < 0.05).