Fig. 6. Nano-MgB₂ inhibited skin infection in vivo.

a Photographs of P. aeruginosa-infected mouse skin treated with or without 10 μg and 50 μg Nano-MgB₂ (n = 3 biologically independent mice). b, c Survival of bacteria from P. aeruginosa-infected mouse skin or spleen taken as in (a) (n = 3 biologically independent mice). d H&E staining of P. aeruginosa-infected mouse skin taken as in (a). Scale bar = 200 μm. e Immunofluorescence staining with the neutrophil cell marker myeloperoxidase (MPO) and macrophage cell marker F4/80 of P. aeruginosa-infected mouse skin taken as in (a). Scale bar = 100 μm. f TNF-α, IL-6, and MCP-1 protein expression detected by CBA MOUSE INFLAMMATION kit in P. aeruginosa-infected mouse skin taken as in (a) (n = 5 biologically independent mice). Data are representative of at least three independent experiments with similar results. Values are the mean ± SEM. One-way ANOVA with Bonferroni post test was used to analyze multiple groups. Source data are provided as a Source data file.