Identified proteins	Fisher's exact test (p<0.02)	Fold change
Coagulation factor V	<0.00010	102.60
Thrombospondin‐1	<0.00010	61.75
Heparin cofactor 2	0.0002	39.90
Apolipoprotein E	<0.00010	38.95
GDH/6PGL endoplasmic bifunctional protein	0.0003	36.10
Antithrombin‐III	<0.00010	33.25
Phosphatidylcholine‐sterol acyltransferase	0.0009	32.30
Carboxypeptidase N catalytic chain	<0.00010	31.35
Plastin‐2	0.0034	28.50
Apolipoprotein C‐III	<0.00010	28.50
Inter‐alpha‐trypsin inhibitor heavy chain H3	<0.00010	27.55
Complement factor I	0.0053	26.60
Profilin‐1	0.0003	22.80
Apolipoprotein B‐100	0.013	22.80
Coagulation factor IX	0.0003	20.90
Tropomyosin alpha‐4 chain	0.0054	10.77
Insulin‐like growth factor‐binding protein complex acid labile subunit	0.014	9.03
Apolipoprotein C‐I	<0.00010	8.21
Transthyretin	0.0095	7.92
Apolipoprotein E	0.0086	7.13
Hemoglobin subunit beta	0.0063	6.49
Serum paraoxonase/arylesterase 1	0.013	6.27
Complement	0.0055	5.95
Fibronectin (Fragment)	<0.00010	5.32
Actin, cytoplasmic 1	0.0012	5.27
Hemopexin	0.0150	5.13
Beta‐enolase	0.0003	‐5.79

Serum proteins (n=27) showing significantly differing abundances (fold change ≥5 (p<0.02) between cats with idiopathic IBD and healthy controls.