Table 1. The differences in various variables between the control and CKD groups
CKD groups (N=27) | ||||||
---|---|---|---|---|---|---|
Parameters | Control (N=17) | Early stagea | Late stageb | P value | ||
SNHR (×10‐2 ppb) | 0.16 (0.15–0.19) | 0.17 (0.14–0.18) | N=34 | 0.20 (0.17–0.24)c | N=16 | 0.035 |
Age (year) | 4.94 (1–7.5) | 9.24 (5.75–13)c | N=34 | 14 (8.75–16)cd | N=18 | <0.001 |
Creatinine (mg/dL) | 1.60 (1.2–1.7) | 2.00 (1.9–2.32) | N=34 | 3.55 (3.07–4.52)cd | N=18 | <0.001 |
BUN (mg/dL) | 22 (19–25.5) | 23 (21.75–31) | N=34 | 40.5 (33–64)cd | N=18 | <0.001 |
Hematocrit (%) | 42.56 (37.56–48.85) | 40.10 (37.15–42.63) | N=34 | 33.86 (26.95–38.4)cd | N=17 | <0.001 |
RBC (106/μL) | 8.63 (7.53–9.65) | 8.29 (7.65–9.31) | N=34 | 7.30 (6.13–8.05)c | N=17 | 0.034 |
Hemoglobin (g/L) | 14.44 (13–16.12) | 13.69 (12.6–14.45) | N=34 | 11.46 (9.5–12.75)cd | N=17 | <0.001 |
Platelet (K/μL) | 223 (133–280) | 283 (219–380) | N=33 | 287 (213–423) | N=17 | 0.125 |
Albumin (g/dL) | 3.60 (3.35–3.75) | 3.48 (3.15–3.7) | N=25 | 3.27 (2.98–3.43) | N=14 | 0.064 |
Phosphate (mg/dL) | ‐ | 4.55 (3.95–5.1) | N=24 | 4.90 (4.2–6) | N=18 | 0.121 |
Total calcium (mg/dL) | ‐ | 10.6 (10.33–11.3) | N=10 | 11.5 (10.5–15) | N=7 | 0.105 |
USG | 1.05 (1.04–1.05) | 1.02 (1.01–1.03) c | N=34 | 1.01 (1–1.02)c | N=18 | <0.001 |
Urinary pH | 6.45 (5.94–6.87) | 6.40 (5.93–6.65) | N=34 | 5.98 (5.93–6.4) | N=18 | 0.030 |
UPC | 0.02 (0.02–0.02) | 0.075 (0.02–0.16)c | N=34 | 0.19 (0.11–1.04)cd | N=18 | <0.001 |
Sodium (mEq/L) | 157. (155–158.7) | 155.65 (154–157.8) | N=24 | 155.25 (153.6–158.9) | N=18 | 0.699 |
Potassium (mEq/L) | 3.96 (3.7–4.03) | 3.84 (3.6–4.03) | N=24 | 4.10 (3.71‐4.3) | N=18 | 0.080 |
Chloride (mEq/L) | 118.3 (117.6–120.5) | 118.1 (116.9–120.3) | N=24 | 118.4 (116.5–122.9) | N=18 | 0.857 |
Variables were tested with Kruskal Wallis Test and represented as the median (inter quartile range, IQR). The post hoc analysis was Dunn's test. Abbreviation: SNHR, serum NTBI‐to‐hematocrit ratio; BUN, Blood urea nitrogen; USG, urine specific gravity; UPC, urine protein‐to‐creatinine ratio a: IRIS stage I and stage II b: IRIS stage III and stage IV c: Achieved significance with control group. d: Achieved significance with early stage group.