Table 2. Weight and hemodynamics data of piglets.
| Variables | Sham (n=7) | Banded (n=6) | Losartan (n=6) |
|---|---|---|---|
| Preoperative weight (kg) | 6.5±1.1 | 5.7±1.5 | 6±1.2 |
| Weight before death (kg) | 25.5±2.4 | 21.9±1.6* | 22.8±1.9* |
| Heart rate (beats/min) | 80±5.6 | 91±7.1* | 85±6.4 |
| Systolic PAP (mmHg) | 17±2.3 | 38.5±6.5* | 26±7.2*# |
| Diastolic PAP (mmHg) | 11±2.1 | 22.5±3.5* | 14.7±3.7*# |
| Mean PAP (mmHg) | 14±1.3 | 29±4.7* | 20.1±6.2*# |
| Systolic ABP (mmHg) | 83.5±1.5 | 89±10 | 87±5 |
| Diastolic ABP (mmHg) | 53.5±4.5 | 62.5±11.5 | 63.3±3.7* |
| Mean ABP (mmHg) | 64.5±2.5 | 71.5±8.7 | 69.5±6.5 |
| Systolic PAP/ABP | 0.21±0.04 | 0.43±0.09* | 0.3±0.07*# |
| Systolic RVP/LVP | 0.27±0.07 | 0.48±0.09* | 0.36±0.07*# |
| CVP (mmHg) | 2.5±1.3 | 5±2.1* | 4.2±1.8 |
| Mean LAP (mmHg) | 6.5±2.5 | 8.2±3 | 7.3±3.2 |
Data are described as mean ± SD. *P<0.05 vs. sham; #P<0.05 vs. banded. PAP, pulmonary artery pressure; ABP, aortic blood pressure; RVP, right ventricular pressure; LVP, left ventricular pressure; CVP, central vein pressure; LAP, left atrial pressure; SD, standard deviation.