Table 1. Cmax, AUC and T1/2 for Irinotecan, sacituzumab Govitecan and trastuzumab deruxtecan.

Drug	Cmax (ng/mL)	AUC (ng*h/mL)	T½ (hours)
Irinotecan 350 mg i.v. (10)	56	451	13.8
Sacituzumab Govitecan (11)	90	2,730	19.7
Trastuzumab deruxtecan (12-14)	1	NA	168

AUC, area under the curve; NA, not available.