Table 5.
A: Main baseline demographics of matched cohorts comparing BP-CCBs with ARBs. A: patients with no prior neuropsychiatric diagnosis. B: patients with a prior neuropsychiatric diagnosisa.
| A: no prior neuropsychiatric diagnosis | B: with prior neuropsychiatric diagnosis | |||
|---|---|---|---|---|
| BP-CCB | ARB | BP-CCB | ARB | |
| Cohort size (n) | 38,305 | 38,305 | 20,673 | 20,673 |
| Age at index (y, SD) | 56.8 (18.1) | 57.9 (16.3) | 54.9 (17.1) | 55.7 (14.5) |
| Sex (M:F %) | 42:58 | 43:57 | 41:59 | 43:57 |
| Race (W,B,O %)b | 52, 30, 18 | 50, 31, 19 | 59, 31, 10 | 57, 33, 10 |
| Blood pressure | 135/77 | 135/77 | 135/78 | 135/78 |
| Body mass index (SD) | 30.1 (7.1) | 30.2 (7.3) | 30.6 (7.7) | 31.2 (7.7) |
| Prior psychotic disorder (%) | 0 | 0 | 3 | 4 |
| Prior affective disorder (%) | 0 | 0 | 32 | 33 |
| Prior anxiety disorder (%) | 0 | 0 | 31 | 32 |
| Prior substance use disorder (%) | 0 | 0 | 31 | 32 |
| Prior sleep disorder (%) | 0 | 0 | 30 | 31 |
| Prior delirium (%) | 0 | 0 | 4 | 4 |
| Prior dementia (%) | 0 | 0 | 2 | 4 |
| Prior movement disorder (%) | 0 | 0 | 5 | 5 |
aSee footnote a to Table 1.
bW: white. B: black. O: other or not known.