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. 2022 May 3;27(8):3286–3293. doi: 10.1038/s41380-022-01581-z

Table 2.

Results of multilevel models with a longitudinal design.

Magical thinking in adulthood (n = 1292)
Model 1 pseudo R2:Level 1:0.114, Level 2:0.120 Model 2 pseudo R2:Level 1:0.114, Level 2:0.119
B SE p B SE p
Fixed effects
 Intercept −0.029 0.132 0.827 −0.030 0.132 0.820
 Age −0.033 0.004 <0.001 −0.033 0.004 <0.001
 Age squared 0.001 0.000 <0.001 0.001 0.000 <0.001
 PRSWGT 0.077 0.024 0.001 0.036 0.031 0.251
 PRSWGT × age 0.003 0.001 0.034
Random effects
 Variance of intercept 0.802 0.019 <0.05 0.802 0.019 <0.05
 Residual variance 0.488 0.008 <0.05 0.488 0.008 <0.05

Estimates (B) with standard errors (SE) of weighted polygenic risk score for schizophrenia (PRSWGT) and age, when predicting standardized scores of magical thinking in adulthood.

“Fixed effects” refer to the classic regression coefficients. “Random effects” refer to the between-individual variation in the intercept and residual variance.

Models 1 and 2 were otherwise identical but, in Model 2, we added the age-interaction of the PRS.

Models were adjusted for sex, childhood family environment (stressful life events, adverse socioeconomic circumstances, unfavorable emotional family atmosphere), and socioeconomic factors in adulthood (level of income, occupational status, educational level).