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. 2022 Nov 29;9:732. doi: 10.1038/s41597-022-01845-x

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — Proteome profiling of HCC cell lines. (a) The identified protein group number of nine HCC cell lines. The cumulative curve was shown on the top in gray. (b) Bar plot showed the number of protein groups detected in different number of HCC cell lines. (c) Bar plot showed the number of protein groups having different number of peptides. (d) Heatmap showed the Pearson correlation coefficients of nine HCC cell lines. (e) Venn diagrams shows the uniquely identified protein groups in this study compared with data reported by Nusinow, D.P. et al.⁷ and Gonçalves, E. et al.⁸. (f) Density plot shows the proteome-transcriptome correlation distribution of protein groups by five HCC cell lines. Different Pearson correlation coefficient ranges are represented by different colours. Representative proteins are marked in the figure.