Table 1.
Descriptive characteristics of patients with colorectal cancer (N = 515) and the prevalence of KRAS mutations.
| Parameter | Value | Percent |
|---|---|---|
| Women, number of patients | 294 | 57.1 |
| Men, number of patients | 221 | 42.9 |
| Age, years, median (lower quartile, upper quartile) | 59 (53, 65) | |
| T∗, number of patients | T1: 8 | 1.55 |
| T2: 52 | 10.10 | |
| T3: 159 | 30.9 | |
| T4: 289 | 56.1 | |
| Tx: 7 | 1.4 | |
| N∗, number of patients | N0: 181 | 35.2 |
| N1: 173 | 33.6 | |
| N2: 100 | 19.4 | |
| N3: 4 | 0.8 | |
| Nx: 57 | 11.1 | |
| M∗, number of patients | M0: 294 | 57.1 |
| M1: 198 | 38.4 | |
| Mx: 24 | 4.7 | |
| KRAS mutations, number of patients | 167 | 32.43 |
| G12A, number of patients | 16 | 3.11 |
| G12C, number of patients | 13 | 2.52 |
| G12D, number of patients | 61 | 11.84 |
| G12R, number of patients | 1 | 0.19 |
| G12V, number of patients | 58 | 11.26 |
| G13D, number of patients | 18 | 3.50 |
| WT, number of patients | 348 | 67.57 |
∗
- staging according to the TNM classification of malignant tumors (7th edition). T, size, and extent of the primary tumor; N, degree of spread to regional lymph nodes; M, presence of distant metastasis, number of patients.