Table 2.
Univariate and multivariate logistic analyses of the association between ALPS-index and VCI, SVCI, and PSCI.
| ALPS-index (%) | Model 1, unadjusted | Model 2a | Model 3b | |||||
|---|---|---|---|---|---|---|---|---|
| OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P | |||
| VCI | 0.914 (0.884–0.945) | <0.001 | 0.912 (0.881–0.944) | <0.001 | 0.868 (0.817–0.921) | <0.001 | ||
| SVCI | 0.937 (0.893–0.976) | 0.003 | 0.927 (0.885–0.972) | 0.002 | 0.863 (0.781–0.954) | 0.004 | ||
| PSCI | 0.900 (0.838–0.966) | 0.002 | 0.890 (0.825–0.960) | 0.002 | 0.816 (0.712–0.935) | 0.003 | ||
ALPS, analysis along the perivascular space; VCI, vascular cognitive impairment; SVCI, cerebral small vessel disease cognitive impairment; PSCI, post-stroke cognitive impairment; OR, odds ratio; CI, confidence interval. aAdjusted for age, gender, and education. bAdjusted for age, gender, education, hypertension, hyperlipemia, diabetes, history of smoking, and Framingham Stroke Risk Profile.