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. 2022 Nov 16;13:1035899. doi: 10.3389/fgene.2022.1035899

TABLE 7.

Genotype distribution in professional soccer players with matches and training injuries for muscle injuries polygenic profile.

Symbol Gene Polymorphism dbSNP Genotype score (Varillas Delgado et al., 2020b) Training injured professional soccer players Match injured professional soccer players p-value
ACE Angiotensin-converting enzyme I/D rs4646994 2 = DD 21 (35.0%) 20 (32.8%) 0.959
1 = ID 29 (48.3%) 31 (50.8%)
0 = II 10 (16.7%) 10 (16.4%)
ACTN3 alpha-actinin-3 c.1747C>T rs1815739 2 = CC 16 (26.7%) 23 (37.7%) 0.291
1 = CT 36 (60.0%) 28 (45.9%)
0 = TT 8 (13.3%) 10 (16.4%)
AMPD1 Adenosine monophosphate deaminase 1 c.34C>T rs17602729 2 = CC 25 (41.7%) 25 (41.0%) 0.119
1 = CT 18 (30.0%) 27 (44.3%)
0 = TT 17 (28.3%) 9 (14.8%)
CKM Muscle-specific creatine kinase c.*800A>G rs8111989 2 = GG 9 (15.0%) ↑ 3 (4.9%) ↓ 0.178
1 = GA 19 (31.7%) 21 (34.4%)
0 = AA 32 (53.3%) 37 (60.7%)
MLCK Myosin Light Chain Kinase c.37885C>A rs28497577 2 = AA 0 (0.0%) 0 (0.0%) 0.009
1 = CA 7 (11.7%) ↓ 19 (31.1%) ↑
0 = CC 53 (88.3%) ↑ 42 (68.9%) ↓
Myosin Light Chain Kinase c.49T>C rs2700352 2 = CC 38 (63.3%) 39 (63.9%) 0.916
1 = CT 19 (31.7%) 18 (29.5%)
0 = TT 3 (5.0%) 4 (6.6%)