Table 2.
Diagnostic performance of the Schistoscope 5.0 for the detection of Schistosoma eggs performed on 487 urines collected at baseline screening
| Conventional microscopy | Schistoscope 5.0 | |||||||
|---|---|---|---|---|---|---|---|---|
| Semiautomated digital microscopy | Automated digital microscopy | |||||||
| Sen (95% CI) | Spec (95% CI) | PPV (95% CI) | NPP (95% CI) | Sen (95% CI) | Spec (95% CI) | PPV (95% CI) | NPV (95% CI) | |
| All samples with S. haematobium infection (N = 166) | 80.1 (73.2–86.0) | 95.3 (92.4–97.4) | 89.8 (84.0–94.2) | 90.3 (87.0–93.2) | 87.3 (81.3–92.0) | 48.9 (43.3–55.0) | 46.9 (41.2–53.0) | 88.2 (83.0–93.0) |
| Low-intensity infection* (n = 129) | 75.2 (67.0–82.3) | – | – | – | 83.7 (76.1-90.0) | – | – | – |
| High-intensity infection† (n = 37) | 97.3 (86.0–100.0) | – | – | – | 100 | – | – | – |
CI = confidence interval; NPV = negative predictive value; PPV = positive predictive value; Sen = sensitivity; Spec = specificity.
*
≤ 50 eggs/10 mL urine.
†
> 50 eggs/10 mL urine.