Table 4.

Multiple linear regression for association between genotype frequency and patients' BMI, after adjustment for parental confounders using two models.

Model	Gene (investigated SNP)	Genotype	Coefficient	Standard error	95 % CI	t	p-value	VIF
Model A
	PPARG rs1801282 (Pro12Ala)	CC-ref.
		CG	−0.09	0.26	−0.61–0.42	0.35	0.71	1.16
		GG	0.18	0.67	−1.13–1.50	0.27	0.78	1.06
	PPARG rs1800571 (Pro115Gln)	CC-ref.
		CA	−0.24	1.15	−2.52–2.02	0.21	0.83	1.07
	PPARG rs3856806 (His447His)	CC-ref.
		CT	−0.04	0.26	−0.55–0.46	0.17	0.85	1.18
		TT	0.94	0.59	−0.22–2.11	1.59	0.11	1.10
	PPARGC1A rs8192678 (Gly482Ser)	CC-ref.
		CT	−0.08	0.22	−0.52–0.35	0.38	0.69	1.28
		TT	0.11	0.28	−0.44–0.66	0.40	0.68	1.26
Model B
	PPARG rs1801282 (Pro12Ala)	CC-ref.
		CG	−0.30	0.32	−0.94–0.33	0.93	0.34	1.16
		GG	−0.23	0.79	−1.80–1.32	0.30	0.76	1.02
	PPARG rs1800571 (Pro115Gln)	CC-ref.
		CA	2.00	1.36	−0.68–4.68	1.46	0.14	1.02
	PPARG rs3856806 (His447His)	CC-ref.
		CT	0.11	0.31	−0.51–0.74	0.36	0.71	1.15
		TT	0.94	0.71	−0.45–2.35	1.32	0.18	1.09
	PPARGC1A rs8192678 (Gly482Ser)	CC-ref.
		CT	−0.18	0.27	−0.71–0.34	0.68	0.49	1.26
		TT	0.02	0.34	−0.65–0.70	0.06	0.94	1.20

CI, confidence interval; Model A, adjustment in accordance to maternal age, parity, weight (devised according to BMI), educational level, and ethnicity; Model B, adjustment in accordance to paternal age, weight (devised according to BMI), and ethnicity; ref., reference (the homozygous genotype of the wild allele was selected as reference); VIF, variance inflation factor.