Table 1.
Minimal inhibitory concentration (MIC)-based comparison of allicin with AmB and FLU.
| Group | C. neoformans H99 | Clinical strains (44) | > ECV (2) | ||
|---|---|---|---|---|---|
| MIC | MICs | MIC50 | MIC90 | MICs | |
| Alliin | > 16 | ||||
| Alliinase | > 16 | ||||
| Allicin | 2 | 1–8 | 2 | 8 | 1–2 |
| AmB | 0.125 | 0.0625–0.5 | 0.125 | 0.25 | 1–2 |
| FLU | 1 | 0.125–8 | 2 | 4 | |
The MIC evaluation criteria were as follows: AmB (100% inhibition of growth), FLU (50% inhibition of growth), and allicin (100% inhibition of growth). The interpretation criteria are described in the “Materials and methods” section.