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. 2022 Nov 16;13:1023164. doi: 10.3389/fimmu.2022.1023164

Table 4.

Median trends in the number of antibodies to orthopoxviruses (ODrel, Me[IQR]) depending on age and VNA.

Age cohort VNA (max dilutions with neutralizing activity)
1. 2. 3. p (Kraskell Wallis criterion)
0 1/5 – 1/10 ≥ 1/20
30-45 n = 72
0.31 [0.29 – 0.40]
n = 15
0.32 [0.28 – 0.46]
n = 5
0.92 [0.59 – 2.98]
0.004*
p (1vs2) = 1.000
p (1vs3) = 0.003*
p (2vs3) = 0.011*
46-80 n = 32
0.49 [0.36 – 0.85]
n = 79
0.94 [0.54 – 1.54]
n = 95
1.92 [1.04 – 2.88]
<0.001*
p (1vs2 ) = 0.011*
p (1vs3)<0.001*
p (2vs3)<0.001*
p (Mann Whitney criterion) <0.001* <0.001* 0.411

*differences are statistically significant (p<0.05).