Table 3.

DCGL, overall graft loss, and mortality rates according to TAC-IPV and RM/NRM status.

	Low-IPV/NRM (n = 452)	High-IPV/NRM(n = 375)	Low-IPV/RM(n = 106)	High-IPV/RM(n = 147)	P-value
DCGL (n, %)	25 (5.5%)§	38 (10.1%)§	6 (5.7%)§	28 (19.0%)*†‡	<0.001
Overall graft loss (n, %)	43 (9.5%)§	51 (13.6%)	13 (12.3%)	32 (21.8%)*	0.002
Mortality (n, %)	24 (5.3%)	17 (4.5%)	8 (7.5%)	9 (6.1%)	0.643

Categorical variables are shown as proportions. ^*P <0.0083 versus low-IPV/NRM group, ^†P <0.0083 versus high-IPV/NRM group, ^‡P <0.0083 versus low-IPV/RM group, ^§P <0.0083 versus high-IPV/RM group.

DCGL, death-censored graft loss; IPV, intra-patient variability; NRM, non-rapid metabolizer; RM, rapid metabolizer; TAC, tacrolimus.