Table 1:
Parameter | Unit | 10 week Enpp1wt | 10 week ENPP1asj | 10 week Enpp1T238A |
---|---|---|---|---|
Calcium | mg/dL | 8.2 ± 1.5 | 9.03±0.5 | 8.0 ± 1.2 |
Phosphate | mg/dL | 6.2± 0.3 | 4.8 ± 0.7** (↓) | 4.7 ± 0.6**(↓) |
PTH | pg/ml | 173 ± 51 | 287 ± 60** (↑) | 277 ± 86**(↑) |
FGF23 | pg/ml | 174 ± 70 | 426 ± 90***(↑) | 320 + 111**(↑) |
PPi | nM | 2262±350 | 99 ± 37*** (↓) | 98 ± 44***(↓) |
Arrows indicated that the reported analytes are significantly above (↑) or below (↓) the corresponding analytes in Enpp1wt mice.
p<0.01,
p<0.001, ANOVA