Table. Summary characterization of pediatric AR clusters.
Cluster | Description | No. of sensitized allergens | Type 2 inflammation | BHR | Airway function impairment | Nasal symptoms | Asthma morbidity |
---|---|---|---|---|---|---|---|
1 (13.3%) | NAR dominant cluster with low type 2 inflammation | +− | + | + | − | + | − |
2 (47.3%) | Intermediate type 2 inflammation and low BHR | ++ | ++ | + | − | ++ | + |
3 (27.0%) | High type 2 inflammation and intermediate BHR | ++ | +++ | ++ | − | ++ | + |
4 (12.4%) | High type 2 inflammation and BHR | ++ | +++ | +++ | + | ++ | ++ |
BHR, bronchial hyper-responsiveness; NAR, non-allergic rhinitis.