Table 7. The different international grading systems (EAACI2006, WAO2010, and AAAAI/ACCAI).
| Grading system | Grade 0 | Grade 1 | Grade 2 | Grade 3 | Grade 4 | Grade 5 |
|---|---|---|---|---|---|---|
| EAACI2006 | Regardless of the severity, any of the following nonspecific symptoms: decreased blood pressure (sensation), sensation of foreign body, fatigue, headache, nausea, vomiting, dizziness, and tachycardia | Regardless of severity if any of the following: abdominal pain, chest discomfort, chest tightness, diarrhea, dysphagia; or, if any of the following and mild severity: asthma, bronchospasm, cough, dysphonia, dyspnea, erythema, rhinitis, urticaria, wheezing, and conjunctivitis | Any of these symptoms when severity is moderate and onset is 15 min or later: asthma, bronchospasm, dyspnea, generalized erythema, generalized pruritus, rhinitis, urticaria, wheezing, conjunctivitis, and laryngeal edema | Any of these symptoms when intensity is moderate and the onset is earlier than 15 min: generalized erythema, generalized pruritus, urticaria, angioedema/laryngeal edema and wheezing; or any of the following regardless of the onset if intensity is severe: asthma, angioedema, bronchospasm, dyspnea, generalized erythema, generalized pruritus, urticaria, flushing, and wheezing | When hypotension or loss of consciousness is present | NA |
| WAO2010 | NA | Only a single organ affected with any of these symptoms in mild reaction: angioedema, erythema, generalized erythema, pruritus generalized, urticaria, flushing, cough, dysphonia, rhinitis, dizziness, syncope, headache, blood pressure decrease (subjective feeling), fatigue, sensation of foreign body, nausea, dysphagia, and tachycardia | When 2 organs are affected with mild severity; or, if any of the following alone with mild severity: asthma, bronchospasm, chest discomfort, chest tightness, wheezing, dyspnea, vomiting, abdominal pain, and diarrhea | If any of the following along with moderate severity: asthma, bronchospasm, chest discomfort, chest tightness, dyspnea, and wheezing; or, if laryngeal edema with mild severity | If any of the following along with severe affection: asthma, bronchospasm, chest discomfort, chest tightness, dyspnea, and wheezing; or if any of the following regardless of severity: hypotension or loss of consciousness | Death |
| AIT | ||||||
| AAAAI/ACAAI | NA | If mild severity, 1 or more of the following: generalized erythema, generalized pruritus, flushing, rhinitis, conjunctivitis, erythema, generalized erythema, urticaria, chest discomfort, chest tightness, angioedema, and laryngeal edema | If any of the following with mild or moderate severity: asthma, bronchospasm, dyspnea, wheezing; or, when moderate severity if any of the following: rhinitis, cough, dysphonia, urticaria, abdominal pain, diarrhea, dysphagia, nausea, vomiting, chest discomfort, and chest tightness | If any of the following along with severe presentation of: asthma, bronchospasm, dyspnea, and wheezing; or, any of the following regardless of the severity of the reaction: hypotension, loss of consciousness | NA | NA |
NA, not applicable.