Skip to main content
. 2022 Nov 30;1276:134690. doi: 10.1016/j.molstruc.2022.134690

Table 2.

Mechanisms of action of 17g, 18c and 18f against SARS-CoV-2.

Compound ID
Conc (µM)
Mode of action
Virus inhibition%
Adsorption Replication Virucidal
17g
125 29.6 ± 8.3 50.0 ± 3.3 47.8 ± 5.1
62.5 26.7 ± 6.65 45.1 ± 1.71 37.3 ± 6.43
31.25 16.7 ± 3.35 38.2 ± 4.29 25.6 ± 5.1
18c
125 44.4 ± 3.87 43.3 ± 3.35 38.9 ± 2.31
62.5 28.9 ± 10.18 38.9 ± 1.91 33.6 ± 6.03
31.25 20.0 ± 3.3 30.0 ± 3.3 22.2 ± 5.1
18f 125 20.0 ± 3.3 40.0 ± 10 53.3 ± 3.35
62.5 13.3 ± 3.35 40.0 ± 3.3 34.4 ± 5.1
31.25 6.7 ± 6.65 31.6 ± 4.27 15.6 ± 13.89