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. 2022 Nov 30;13:7365. doi: 10.1038/s41467-022-35136-1

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — a Plasmids and plasmid-mediated resistance genes are represented in the heatmap by red, green, yellow, and blue bands, respectively. b Pairwise comparisons of the plasmids harboring the bla_CTX-M, bla_CMY-2, bla_TEM-1, mphA/ermB, and mcr-1 genes. Four replicons of plasmids, including pSH15sh99, pH267-2, and pSH13D178-1 of IncB/O/K/Z; pKSR100, p183660, and pSH13D178-2 of IncFII; pV233-b, pSH13D178-3, and pSH11sh418-1 of IncI1-(Alpha); and pHNSHP45 and pSH267-1 of IncI2, were selected for pairwise comparisons. Source data are provided as a Source Data file. cef^Razi^R coresistance to ceftriaxone and azithromycin, col^R resistance to colistin.