Comparison 1. High versus low blood pressure target.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1.1 Acute kidney injury	2	487	Risk Ratio (M‐H, Fixed, 95% CI)	1.30 [0.81, 2.08]
1.2 Cognitive deterioration	2	389	Risk Ratio (M‐H, Random, 95% CI)	0.82 [0.45, 1.50]
1.3 All‐cause mortality	3	737	Risk Ratio (M‐H, Random, 95% CI)	1.33 [0.30, 5.90]
1.5 Quality of life	1		Risk Ratio (M‐H, Fixed, 95% CI)	Totals not selected
1.6 Acute ischaemic stroke	2	426	Risk Ratio (M‐H, Random, 95% CI)	1.29 [0.07, 23.63]
1.7 Length of hospital stay	2	540	Mean Difference (IV, Fixed, 95% CI)	1.25 [0.78, 1.73]
1.8 Renal replacement therapy	2	486	Risk Ratio (M‐H, Fixed, 95% CI)	1.33 [0.47, 3.77]
1.9 Delirium	1		Risk Ratio (M‐H, Fixed, 95% CI)	Totals not selected
1.10 Perioperative transfusion of blood products	2	540	Mean Difference (IV, Fixed, 95% CI)	0.10 [‐0.13, 0.34]
1.11 Perioperative myocardial infarction	3	734	Risk Ratio (M‐H, Random, 95% CI)	0.91 [0.26, 3.16]