FIG. 5.
Survival curves of C3H (A and B), C57BL/6 (C), and BALB/c (D and E) mice vaccinated with plasmid encoding GRA1, GRA7, or ROP2 or with control plasmid without insert (three 100-μg doses of DNA with 3-week interval) and challenged perorally between 6 and 9 weeks after the third DNA dose. T. gondii cysts (strain IPB-G) were administered to C3H (50 cysts in panel A), C57BL/6 (10 cysts in panel C), and BALB/c mice (200 cysts in panel D and 50 cysts in panel E) mice. T. gondii 76K was used for challenging C3H mice (50 cysts in panel B). The number of mice for each condition is indicated in parentheses.