Figure 5.

Functional nucleic acids actuation by chemical or physical cues. (a) Shape transitions of nanosized pinching DNA origami devices by a variety of chemical cues, such as ATP, Na⁺, Ag⁺, and miRNA. Reproduced with permission from ref (84). Copyright 2011, Nature Publishing Group. (b) DNA origami nanocaliper actuated through the incorporation of the pH-responsive i-motif sequence. Reproduced with permission from ref (85). Copyright 2022, Royal Society of Chemistry. (c) Schematic and TEM image of the light reconfigurable DNA origami sphere. Reproduced with permission from ref (87). Copyright 2015, Royal Society of Chemistry.