Table 2.
Two-sample t-test results of the whole-brain intrinsic functional connectivity of bilateral insula between the OCD and HC groups
| Seed Region | Area | BA | L/R | Voxels | MNI | T peak-values | P uncorrected | P FWE−corrected | ||
|---|---|---|---|---|---|---|---|---|---|---|
| X | Y | Z | ||||||||
| Left insula | ||||||||||
| OCD > HC | Precuneus/Inferior Parietal Lobule | 31/7 | L&R | 982 | -15 | -54 | 42 | 5.83 | 0.000 | 0.000* |
| Supplementary motor area | 6 | R | 242 | 15 | -6 | 57 | 3.84 | 0.001 | 0.019* | |
| Right insula | ||||||||||
| OCD > HC | Precuneus/Inferior Parietal Lobule | 31/7 | L&R | 970 | -15 | -54 | 42 | 5.35 | 0.000 | 0.000* |
| Supplementary motor area | 6 | L&R | 439 | -15 | -15 | 54 | 5.45 | 0.000 | 0.000* | |
| OCD < HC | Lingual Gyrus | 30/19 | L&R | 346 | 36 | -42 | 3 | 4.04 | 0.000 | 0.002* |
Abbreviations: OCD: obsessive-compulsive disorder; HC: healthy control; BA: Brodmann areas; MNI: Montreal Neurological Institute; R: right; L: left; FWE: familywise error correction
* P < 0.025 with FWE correction.