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Schematics of autologous reconstitution of human solid tumors. PDX is patient derived xenoplants, BMC bone marrow cells, and TME tumor microenvironment. The recipient mice (e.g. NOG, NSG, NSG-HLA-A2, NSG-IL-6, etc.) can vary depending on the aims of the experiment. Both engraftment of the PDX tumor and BMC should be performed with NOG/NSG mice.
