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. Author manuscript; available in PMC: 2024 Jan 1.
Published in final edited form as: Neurosci Lett. 2022 Nov 9;792:136959. doi: 10.1016/j.neulet.2022.136959

Figure 2. In male rats, sleep disruption caused by lightphase gentle handling elicits greater stress than SD induced by lightphase noise and gentle handling does not increase weight gain.

Figure 2.

(A) Experimental design. Change in time spent (B) awake or asleep [C-D: non-rapid eye movement (NREM) sleep and REM sleep], (E-F) cumulative weight gain and food intake during the 9d treatment, (G) plasma corticosterone, and (H) change in physical activity in male rats that slept undisturbed (control (C)) or had sleep disruption (8h/d during the lightphase) for 9-days due to gentle handling (GH) or noise (N). Panel A: arrows indicate bodyweight and food intake measurements prior to beginning treatments at 0600h. Different letters indicate treatments were significantly different (P < 0.05). Data expressed as mean±SEM. n=7–8/group.