Fig. 1.

Main molecular targets for cannabidiol (CBD) in Parkinson's disease (PD). Cannabinoid receptors (CB1/CB2), transient receptor potential cation channel subfamily V member 1 (TRPV1), Wnt/GSK-3β (Wnt/glycogen synthase kinase 3 beta pathway), nerve growth factor (NGF), neurotrophic tyrosine kinase receptor member (TrkA), Janus kinase (JAK), signal transducer and activator of transcription proteins (SATAxin3), nicotinamide adenine dinucleotide (NADH), adenomatous polyposis coli (APC), casein kinase 1 (CK1), beta-catenin (β-catenin), nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB).