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IF staining patterns in C3G. Staining for C3c in DDD reveals the characteristic confluent granular to linear staining of GBMs (a), with occasional linear TBM staining (b). Mesangial staining in all cases of C3G (including DDD) can be quite variable ranging from discrete, large rounded deposits (a) to coarsely granular (c) or confluent granular, all with variable accentuation of capillary walls. All panels: anti-C3c fluorescein isothiocyanate-conjugate, ×400.
