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. 2022 Oct 17;63(2 Suppl 3):E174–E188. doi: 10.15167/2421-4248/jpmh2022.63.2S3.2759

Tab. IX.

Sources and neurological implications of vitamins B1, B6 and B12.

Vitamin Sources Coenzyme for Deficiency symptoms Implications in nervous system Reference
B1 (thiamine) Fish, beans, lentils, cereals, yogurt, sunflower seeds, cereals Pyruvate dehydrogenase, alpha-ketoglutarate dehydrogenase, transketolase Beriberi, polyneuritis Energy supply to nerve cells for synthesis of nucleic acids, neurotransmitters, and myelin [95, 96, 97]
B6 (pyridoxine) Salmon, tuna, beef liver, chicken, leafy greens, orange, banana, papaya, cantaloupe Cystathionine-beta-synthase/lyase, serine-hydroxymethyl transferase, aromatic L-amino acid decarboxylase Cognitive impairment, depression, premature aging of neurons Metabolism of DNA/RNA, amino acids and neurotransmitters [98]
B12 (cobalamin) Dairy products, fish, poultry, eggs, meat Methionine synthase, methylmalonyl CoA mutase Cognitive impairment, impaired neurotransmitter production, polyneuritis, subacute combined spinal cord sclerosis Metabolism of nucleic acids, fatty acids, amino acids, neurotransmitters, myelin [99]