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. 2022 Oct 17;63(2 Suppl 3):E56–E64. doi: 10.15167/2421-4248/jpmh2022.63.2S3.2747

Tab. III.

Studies on the effects of Mediterranean diet on metabolic syndrome.

Authors Type Effects of Mediterranean diet
Kastoroni et al. [78] Meta-analysis
(Number of studies: 50; n: 534,906)
0.42 cm ↓ waist circumference
1.17 mg/dL ↑ HDL
6.14 mg/dL ↓ TAG
2.35 mm Hg ↓ systolic and 1.58 mm Hg ↓ diastolic BP
Huo et al. [79] Meta-analysis
(Number of studies: 9; n: 1178)
0.30% ↓ HbA1c
0.72 mmol/L ↓ FPG
0.55 μU/mL ↓ fasting insulin
0.14 mmol/L ↓ total cholesterol
0.29 mmol/L ↓ TAG
1.45 mm Hg ↓ systolic and 1.41 mm Hg ↓ diastolic BP
Richard et al. [80] Original research
(n: 26 males)
C-reactive protein (CRP) ↓
IL-6, IL-18 and TNF-α ↓
≥8.5 cm waist circumference ↓
IL-6 and IL-18 ↓
Moosavian et al. [81] Systematic review
(Number of studies: 10; n: 856)
Improved body measurements, plasma lipid profile and glucose regulation
Mayneris-Perxachs et al. [82] Original research
(n: 424)
Incidence, reversion and prevalence of metabolic syndrome ↓
Pavić et al. [83] Original research
(n: 124)
HDL ↑ and systolic BP ↓
The Mediterranean diet was effective for the components of metabolic syndrome
Meslier et al. [84] Original research
(n: 82 healthy overweight and obese participants)
Plasma cholesterol and LDL ↓
Insulin sensitivity ↑
Systemic inflammation ↓

↓: Reduction; ↑: Enhancement