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. 2022 Jan 12;2(1):vbac001. doi: 10.1093/bioadv/vbac001

Table 1.

Number of interactions (Ni), compounds (c) and proteins (p), and network density D = Ni/(c × p) in the E.coli and human network after different filtering steps

Dataset E.coli Human
Number of interactions, density STITCH network confidence threshold =0.4

  • 99 487

  • (c = 24 602 p = 2562)

  • D = 1.58E-3

  • 1 026 207 (c = 410 253, p = 9047)

  • D = 0.28E-3
Number of interactions, density metabolic network after cleanup

  • 6894

  • (c = 177, p = 1906)

  • D = 2.04E-2

  • 44 322

  • (c = 2115, p = 7542)

  • D = 0.28E-2
Number of interactions, density without single (degree =1) interactions

  • 6353

  • (c = 160, p = 1381)

  • D = 2.88E-2

  • 42 158

  • (c = 1598, p = 5885)

  • D = 0.45E-2

Note: As node degree =1 interactions were not considered in the biclique computations (as they cannot contribute to our predictions), we list them separately.