Fig. 5.

Symbolic representation of the 16 × 16 correlation matrix of module genes with strongest correlation with the biologically known genes MSH2 and MSH6. The color of the symbols corresponds to the absolute correlation for that pair. The symbol is a triangle when the correlation between the pair is negative, and the symbol is a square when the correlation is positive. The text color of the labeled genes corresponds to the principal component loading. The lines leading from a module variable to the outcome % Tumor Invasion are dotted when the correlation with invasion is negative and solid when the correlation is positive, and the line color indicates the magnitude of the correlation